Skeletal muscle weakness in osteogeneis imperfecta mice
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چکیده
منابع مشابه
Skeletal muscle weakness, fatigue and sarcoidosis.
S arcoidosis is a multisystem granulomatous disorder that may involve many organs. Beside organ specific symptoms, non-specific constitutional complaints such as fatigue and general weakness are frequent. The granuloma formation in sarcoidosis is driven by an array of cytokines such as tumour necrosis factor (TNF)-a, interleukin (IL)-6, interferon (INF)-c and others. High circulating levels of ...
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BACKGROUND Increasing arginine (Arg) availability reduces atrophy in cultured skeletal muscle cells. Supplementation with its metabolic precursor citrulline (Cit) is more effective at improving skeletal muscle Arg concentrations. OBJECTIVE We tested the hypothesis that Cit supplementation would attenuate skeletal muscle atrophy and loss of function during hindlimb immobilization in mice. ME...
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Introduction: Ursolic Acid (UA) is a lipophilic triterpenoid compound, found in large amounts in apple peel. Anabolic effects of UA on the skeletal muscle and the role of this tissue as a key regulator of systematic aging aroused this question in mind whether UA might amend skeletal muscle performances such as myoglobin expression and also whether it switches skeletal muscle fibers from glyc...
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Over a century ago Duchenne summarized his life's work in the third edition of his famous book De L'electrisation Localisee (1872), which laid the foundation of electrophysiology of muscle and clinical myology. Primary muscle diseases are ad mittedly uncommon but, for the sufferers and their families, of grave import since for most no effec tive therapy is as yet available. However, skeletal ...
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Estrogens play a key role in an extensive range of physiological functions in various types of tissues throughout the body in females. We previously showed that estrogen insufficiency caused muscle weakness that could be rescued by estrogen administration in a young female ovariectomized (OVX) mouse model. However, long-term estrogen replacement therapy increases risks of breast cancer and card...
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ژورنال
عنوان ژورنال: Matrix Biology
سال: 2010
ISSN: 0945-053X
DOI: 10.1016/j.matbio.2010.06.006